Although a decade has passed since the discovery, the nature of water masers from the nuclei of galaxies is not well known. The energy emitted in the 22 GHz water rotational line for such sources is about 100-1000 solar luminosity if isotropic emission is assumed. A collision-collision pumping model has been proposed to account the high luminosity of the extragalactic water masers but it is not necessarily successful. The water maser cloud must lie near the nucleus of galaxies. Such molecular clouds near the nucleus must be related with nuclear activity of these galaxies as a source of blackhole. One of intriguing phenomenon discovered recently is extreme high-velocity water maser emission (about 1000 km/s) in NGC 4258 (Nakai et al. 1993; Nature 361, 45). The extreme high- velocity components can be seen at both low- and high-frequency sides and the emission spikes spread in the width of about 200 km/s. No emission between high-velocity and central components are observed in the width of about 600 km/s. One of the possible models to account this phenomena is the rotating disk model in which a gas ring rotates with a velocity of 1000 km/s around the blackhole of about 10^8 solar mass. The extreme velocity components come from the parts of the ring moving toward and away from us, so that the Dopper velocity observed is the speed of the rotation of the disk. The observations of thermal emission of water molecules at the far-infrared wavelengths, for example, J(K,K)=2(1,2)-1(0,1) transition at 179.52 micron, if detecetd, restrict the size of the molecular cloud with water maser emission and discriminate one from the other possible mechanisms for the extreme high-velocity phenomena. For comparison, the observation of normal water maser flare sources as IC 10 is also included.